High quality competitive price Calcium antagonists/Calcium Channel Blockers Cilnidipine 132203-70-4 CAS NO.132203-70-4

1. Quality Features:

   • High Lipophilicity: Sinidigitam has high lipophilicity, which allows it to better penetrate cell membranes, thereby achieving lasting and stable blood pressure reduction .
   • Dual Channel Antagonism: Sinidigitam not only antagonizes the L-type calcium channels in vascular smooth muscle but also acts on the N-type calcium channels in sympathetic nerve terminals. This dual-channel antagonism helps to reduce blood pressure without significantly increasing heart rate .

2. Manufacturing Advantages:

   • Simplified Process Route: The production process of Cilnidipine has a short reaction sequence and a simplified process route, which helps to improve production efficiency 
   • Mild Reaction Conditions: The mild reaction conditions during the production process help to protect the active ingredients of the product, ensuring the stability and effectiveness of the final product

3. Application Advantages:

   • Broad Clinical Application: Sinidigitam has been widely recognized in Japan and East Asia for the treatment of hypertension and related symptoms, such as chronic non-bacterial inflammation and postoperative pain management .
   • Improved Cardiac and Renal Function: Sinidigitam can improve left ventricular hypertrophy, prevent hypertensive heart disease, and reduce intraglomerular pressure to protect renal function .
   • Reduced Adverse Reactions: Compared with other calcium antagonists, Sinidigitam controls blood pressure without increasing heart rate and can prevent adverse reactions such as peripheral edema .

Why you should choose us

1.Good quality,the Cilnidipine we manufacture has a higher purity which could reach to 99.6%.
2.Mature technology brings you a competitive price
3.Various highly customized solutions  satisfy your demands
4.24-hours online service,get the information and quotation whenever you want.
5.Well trained stuff help you choose and get waht you want,even though you are the first time to purchase abroad.
6.Various payment items accepted(Cash,T/T,LC,etc)

Miedykol is a biopharmaceutical science and technology company that specializes in the best-quality cellulose, starch and their derivative products for pharmaceutical, nutraceutical, food, detergent and cosmetics uses. Enjoying the independent biopharmaceutical technology, we also manufacture and supply the high-class active pharmaceutical ingredients (APIs) that have been successfully and generally used in clinical medications as well as pharmaceutical intermediate. Established in 2020, we have grown to become a leader in pharmaceutical excipient and APIs markets by providing our global customers with the sustainable quality products, profitable solutions, and considerate services that considerably benefit our customers and partners. Our commitment to “Always Looking for Nature” has helped us build strong relationships with our customers and partners.

Miedykol was founded by Mikem (Shandong) Biopharmaceutical Science and Technology Co., Ltd. in 2020 with the vision of creating a healthy world for all. It is a brand by Mikem Chemical Ltd. Co., a speciality chemicals supplier and solutions provider headquartered in America who embraces the vision of better living with green chemistry. Over the years, we have grown into an impressively influential player who is capable of sending our products to every corner of the world through the automatic production, packaging system, on-stop delivery and transportation service. Today, we continue to innovate and expand our offerings to meet the evolving needs of our customers.